Abstract Background Impaired p53 function is one of the central molecular features of a tumor cell and even a partial reduction in p53 activity can increase the cancer risk in mice and men.From a therapeutic perspective it is noteworthy that tumor cells often become addicted to the absence of p53 providing a rationale for developing p53 reactivatin
In the last decades artificial recharge has attracted the attention of many countries where groundwater has been depleted or as a means of enhancing aquifer recharge where natural recharge is being severely affected by climate change.In this work, mathematical models depicting the flow of water within a fractured aquifer with permeable and impermea
Irina Saburova and her place in the emigration space The life of some writers-emigrants developed in such a way that it is difficult to clearly ascribe them to one of the Armoire waves of emigration.This question comes up quite often when considering the artists who belong to the first and second wave of migration.The emigrants found themselves out
The Yellowbilled Oxpecker, long believed extinct as a breeding species in the Republic of South Africa has been recorded regularly in the Kruger National Park since 1979.The first definite indication of breeding was recorded in January 1984, and final confirmation of POWDER BURN 2.0 ORANGE SLICE breeding was observed in December 1985.The recovery o
Fungal secondary metabolites (SMs) represent an invaluable source Girls Fall Casual Dress of therapeutic drugs.Genomics-based approaches to SM discovery have revealed a vast and largely untapped biosynthetic potential within fungal genomes.Here, we used the publicly available fungal genome sequences from the NCBI public database, as well as tools s